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Bullet Some facts about Diabetes
Bullet Know basics of diabetes
Bullet What is Type 2 diabetes?
Bullet Take control of your Type 2 diabetes
Bullet How Metformin helps?
Bullet What are the consequences of high blood sugar?

What is Type 2 diabetes?

Old terminology for Type 2 diabetes was Non-Insulin Dependent Diabetes Mellitus (NIDDM) or adult-onset diabetes. Type 2 diabetes accounts for about 90%-95% of all diagnosed cases of diabetes in America.

Unlike Type 1 diabetes, where pancreas does not function properly and thus does not produce insulin, in Type 2 diabetes pancreas is still able to produce insulin at diagnosis in most people. However, the insulin produced is not able to do its primary job, which is to help the body cells to convert the glucose into energy. This is mainly due to problem in insulin receptors on the cells which act as a gate for glucose to enter the cells. This condition is called insulin resistance.

As a result, the presence of glucose in the blood stream is at a higher than normal level. A build up of glucose in the blood is known as hyperglycemia. Hyperglycemia is the trademark characteristic of diabetes. The goal of therapy is to control and manage the excessive sugar in the blood.

Also pancreas keep on making the insulin in an effort to utilize the excessive glucose and thus this can lead to a condition called hyperinsulinemia (high circulating level of insulin). Hyperinsulinemia can lead to cardiovascular and other disorders.

 

Important Safety Information about RIOMET®

RIOMET as monotherapy, is indicated, as an adjunct to diet and exercise, to improve glycemic control in patients 10 years of age and older with type 2 diabetes. RIOMET may be used concomitantly with a sulfonylurea or insulin to improve glycemic control in adults (17 years of age and older).

RIOMET is contraindicated in patients with renal disease or dysfunction, acute or chronic metabolic acidosis, including diabetic ketoacidosis or known hypersensitivity to Metformin hydrochloride.

RIOMET should be avoided in patients >= 80 years old (unless measured creatinine clearance is normal), with impaired hepatic function, excessive alcohol intake (chronic or acute), or in the presence of any condition associated with hypoxemia, dehydration, or sepsis.

Temporarily discontinue in patients receiving intravascular iodinated contrast materials for radiologic studies. Diarrhea, nausea, vomiting, abdominal bloating, anorexia, or flatulence may occur, especially during initiation of therapy.

Not recommended for pediatric patients (under 10 years of age) or pregnant women.

Hypoglycemia does not occur in patients receiving RIOMET alone under usual circumstances of use. Hypoglycemia could occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during concomitant use with other glucose-lowering agents (such as sulfonylureas and insulin) or ethanol.

Please see full Prescribing Information, including boxed WARNING regarding lactic acidosis

Please consult with your healthcare professional to see if RIOMET is right for you. The content of this Web site is not a substitute for professional medical advice and should not be interpreted as treatment recommendations or relied on for medical diagnosis or treatment.